Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats

Figure 3 Histopathological examination of liver in rats with regular or high-fructose feeding. Lipid accumulation in: (A) C_PV rats; (B) F_PV rats; (C)F_{PV + LA}; (D) F_PLPS; and (E) F_{PLPS + LA} rats. CD-68 positive cell infiltration in: (F) C_PV rats; (G) F_PV rats; (H) F_{PV + LA}; (I) F_PLPS; and (J) F_{PLPS + LA} rats. Slides were stained with hematoxylin and eosin (A-E) and immunostained with an anti-CD68 antibody (F-J). Arrows indicate CD68 positive cells. C: Regular diet; F: High-fructose enriched diet; LA: Lipoic acid; LPS: Lipopolysaccharides; CV: Central vein.