Prognostic value of preoperative mean corpuscular volume in esophageal squamous cell carcinoma

Table 1 Clinicopathological parameters and preoperative mean corpuscular volume n (%)

Characteristics	Case numbers	Preoperative MCV		P valuePearson’sχ2test
		Low	High
Age, yr (mean ± SE)	58.2 ± 9.2
≤ 65	231	184 (79.7)	47 (20.3)
> 65	67	55 (82.1)	12 (17.9)	0.660
Gender
Male	230	176 (76.5)	54 (23.5)
Female	68	63 (92.6)	5 (7.4)	0.003
BMI, kg/m2 (mean ± SE)	22.3 ± 3.2
≤ 20	65	46 (70.8)	19 (29.2)
> 20 and ≤ 25	180	144 (80.0)	36 (20.0)
> 25	53	49 (92.5)	4 (7.5)	0.017
Smoking index	440.1 ± 483.1
≤ 400	171	141 (82.5)	30 (17.5)
> 400	127	98 (77.2)	29 (22.8)	0.257
Preoperative RBC, × 1012/L (mean ± SE)	4.5 ± 0.6
≤ 4.01	56	31 (55.4)	25 (44.6)
> 4.0	242	208 (86.0)	34 (14.0)	< 0.001
Preoperative albumin, g/L (mean ± SE)	42.9 ± 4.6
≤ 432	149	115 (77.2)	34 (22.8)
> 43	149	124 (83.2)	25 (16.8)	0.191
pT status, UICC7th (mean ± SE)
T1	33	31 (93.9)	2 (6.1)
T2	52	44 (84.6)	8 (15.4)
T3	213	164 (77.0)	49 (23.0)	0.051
N0	138	116 (84.1)	22 (15.9)
N1	89	67 (75.3)	22 (24.7)
N2	51	42 (82.4)	9 (17.6)
N3	20	14 (70.0)	6 (30.0)	0.250
Histologic grade
G1	94	71 (75.5)	23 (24.5)
G2	156	127 (81.4)	29 (18.6)
G3	48	41 (85.4)	7 (14.6)	0.324
pTNM stage (UICC7th)
Stage I	37	32 (86.5)	5 (13.5)
Stage II	120	100 (83.3)	20 (16.7)
Stage III	141	107 (75.9)	34 (24.1)	0.191
Tumor location
Upper	48	37 (77.1)	11 (22.9)
Middle	150	125 (83.3)	25 (16.7)
Lower	100	77 (77.0)	23 (23.0)	0.393

¹Normal limit of red blood cell count;

²Mean value of preoperative hemoglobin. MCV: Mean corpuscular volume; Low: Low preoperative MCV (≤ 95.6 fl); High: High preoperative MCV (> 95.6 fl); BMI: Body mass index; RBC: Red blood cell; UICC: Union for International Cancer Control.