Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis

Figure 5 Expression and distribution of interleukin-22 and its related proteins in human colonic tissues from patients with inactive ulcerative colitis, active ulcerative colitis, and ulcerative colitis with dysplasia, as detected by immunohistochemistry (× 200). A1-A3: Expression and distribution of interleukin (IL)-22 in inactive ulcerative colitis (UC), active UC, and UC with dysplasia tissues; B1-B3: Expression and distribution of IL-23 in inactive UC, active UC, and UC with dysplasia tissues; C1-C3: Expression and distribution of IL-22R1 in inactive ulcerative colitis (UC), active UC, and UC with dysplasia tissues; D1-D3: Expression and distribution of p-STAT3 (S727) in inactive UC, active UC, and UC with dysplasia tissues.