Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis

Figure 3 Expression and distribution of interleukin-22 and related proteins in human colonic tissues from controls and patients with chronic and initial ulcerative colitis as detected by immunohistochemistry (× 200). A1-A3: Expression and distribution of interleukin (IL)-22 in ulcerative colitis (UC) tissues from the control, chronic UC, and initial UC groups; B1-B3: Expression and distribution of IL-23 in UC tissues from the control, chronic, and initial UC groups; C1-C3: Expression and distribution of IL-22R1 in UC tissues from the control, chronic, and initial UC groups; D1-D3: Expression and distribution of p-STAT3 in UC tissues from the chronic and initial UC groups.