Overexpression of carbonic anhydrase II and Ki-67 proteins in prognosis of gastrointestinal stromal tumors

Figure 2 Analysis of survival rates (Kaplan-Meier) and comparison of survival rates in gastrointestinal stromal tumors groups (log-rank test). A: The highest survival rate was found in those patients that received complete tumor resection and postoperatively took imatinib (400 mg/d), while in those patients not receiving complete tumor resection and postoperative imatinib, the survival rate was lowest (log-rank P = 0.000). 1: Resected completely with imatinib administrated postoperatively, 2: Resected completely without imatinib administrated postoperatively, 3: Resected incompletely with imatinib administrated postoperatively, 4: Resected incompletely without imatinib administrated postoperatively; B: The survival rates in carbonic anhydrase (CA) II-positive group were significantly higher than those in negative groups (CA II, log-rank P = 0.000); C: The survival rates in Ki-67-positive group were higher than those in negative groups (Ki-67, log-rank P = 0.004); D: The survival rates in CD117-positive group were significantly higher than those in negative groups (CD117, log-rank P = 0.000); E: The higher survival rates were found in those patients that received complete tumor resection (R0) (R0, log-rank P = 0.000); F: The higher survival rates were found in those patients with National Institutes of Health (NIH) high risk (NIH risk, log-rank P = 0.006).