Annexin A1: A new immunohistological marker of cholangiocarcinoma

doi:10.3748/wjg.v19.i16.2456

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Apr 28, 2013 (publication date) through Feb 14, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2013; 19(16): 2456-2465
Published online Apr 28, 2013. doi: 10.3748/wjg.v19.i16.2456

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Figure 3 Illustration of the comparative immunohistochemical stains in 3 representative cases. The 3 representative cases include tubular type cholangiocarcinoma (CCA) (Tub CCA), papillary type CCA (Pap CCA) and hepatocellular carcinoma (HCC). Immunopositivity of cytokeratin 7 (CK7), annexin A1 (ANXA1), hepatocyte paraffin 1 (HepPar1) and alpha-fetoprotein (AFP) appeared as brown cytoplasmic staining of tumor cells, while positivity to carbohydrate antigen 19-9 (CA19-9) appeared as cytoplasmic and luminal staining of tumor (magnification, × 40). Noted that CCA are CK7⁺/CA19-9⁺/ANXA1⁺ and HCC is HepPar1⁺/AFP⁺/ANXA1^-. -: Negative result; +: Positive result.

Citation: Hongsrichan N, Rucksaken R, Chamgramol Y, Pinlaor P, Techasen A, Yongvanit P, Khuntikeo N, Pairojkul C, Pinlaor S. Annexin A1: A new immunohistological marker of cholangiocarcinoma. World J Gastroenterol 2013; 19(16): 2456-2465
URL: https://www.wjgnet.com/1007-9327/full/v19/i16/2456.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i16.2456