Effects of Nigella sativa on outcome of hepatitis C in Egypt

Table 2 Laboratory data assessment at baseline and after treatment

Parameter	Base line	After 3 mo treatment	P value
Hemoglobin (g%)	11.8 ± 2.1	12.2 ± 2.2	0.1
RBCs (× 106/μL)	4.13 ± 0.9	4.3 ± 0.9	0.001
WBCs (× 103/μL)	6.4 ± 2.1	5.6 ± 2.2	0.013
Platelets (× 103/μL)	167.7 ± 91.2	198.5 ± 103	0.004
Hematocrit (%)	35.5 ± 6.3	37.3 ± 6.3	0.056
ALT (IU/L)	35.0 ± 15.7	41 ± 24.4	0.255
AST (IU/L)	40.9 ± 30.4	46.8 ± 32.2	0.307
Total protein (g/dL)	7.1 ± 0.7	7.5 ± 0.8	0.001
Albumin (g/dL)	3.5 ± 0.9	3.69 ± 0.9	0.008
Direct bilirubin (mg/dL)	0.5 ± 0.8	0.57 ± 1.5	0.745
Total bilirubin (mg/dL)	1.46 ± 1.5	1.36 ± 1.3	0.428
Prothrombin time (s)	14.1 ± 2.7	13.8 ± 2.2	0.562
INR	1.18 ± 0.2	1.2 ± 0.2	0.974
BUN (mg/dL)	13.5 ± 6.2	14.1 ± 5	0.540
Creatinin (mg/dL)	0.99 ± 0.4	0.88 ± 0.2	0.102
Serum AFP (IU/mL)	5.07 ± 1.8	4.67 ± 2.3	0.194
Sodium (mmole/L)	135.5 ± 6.1	133.5 ± 6	0.064
Potassium (mmole/L)	4.1 ± 0.5	4 ± 0.5	0.350
TAC (mmol/L)	1.35 ± 0.5	1.61 ± 0.6	0.001
Fasting blood sugar (mg/dL)	104.03 ± 43.4	92.1 ± 31.3	0.001
Post prandial blood sugar (mg/dL)	143.67 ± 72.6	112.1 ± 42.9	0.001
PCR (copies)	380808.7 ± 610937	147028.2 ± 475225.6	0.001

Paired t-test for all parameters, median test (equivalent to Wilcoxon matched pairs test) for polymerase chain reaction (PCR) levels. RBCs: Red blood cells; WBCs: White blood cells; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; INR: International normalized ratio; BUN: Blood urea nitrogen; AFP: α-fetoprotein; TAC: Total antioxidant capacity.