Effect of biliary drainage on inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats

Figure 5 Representative immunohistochemical analysis of CD14 in rat liver tissues of sham operation, obstructive jaundice, internal and external biliary drainage groups. A: CD14-immunoreactivity was detected mainly in the membrane of Kupffer cell on the edge of liver sinusoid and portal areas. There was slight expression of CD14 in sham operation (SH) rats; B: 14 d after bile duct ligation, the CD14-immunoreactivity became stronger as compared to SH rats; C: After relief of obstructive jaundice (OJ) by internal biliary drainage (ID), the expression of CD14 was markedly suppressed; D: The expression of CD14 in external biliary drainage (ED) rats was still at a high level; E: Comparison of mean absorbance values of CD14 in liver tissues among the four groups. IHC: Immunohistochemical.