Effect of biliary drainage on inducible nitric oxide synthase, CD14 and TGR5 expression in obstructive jaundice rats

Figure 3 Representative immunohistochemical analysis of inducible nitric oxide synthase in rat liver of sham operation, obstructive jaundice, internal and external biliary drainage groups. A: There was rare expression of inducible nitric oxide synthase (iNOS) in sham operation (SH) group; B: 14 d after bile duct ligation, the iNOS-immunoreactivity became stronger as compared with SH group; C: After relief of obstructive jaundice (OJ) by internal biliary drainage (ID), the expression of iNOS was markedly suppressed; D: The expression of iNOS obviously increased in rat liver of external biliary drainage (ED); E: Comparison of mean absorbance values of iNOS in rat liver tissues among the four groups. IHC: Immunohistochemical.