Effect of Helicobacter pylori eradication on serum ghrelin and obestatin levels

Table 2 Ghrelin and obestatin changes for normal weight and overweight patients after Helicobacter pylori eradication treatment

	Ghrelin initial, pg/mL	Ghrelin week 8, pg/mL	P value1	Obestatin initial, pg/mL	Obestatin week 8, pg/mL	P value1
H. pylori eradicated BMI-NW	58.8 ± 18.6	57.5 ± 22.0	0.46	759 ± 452	865 ± 456	0.08
H. pylori eradicated BMI-OW	68.8 ± 20.3	54.1 ± 17.1	0.002a	774 ± 413	975 ± 565	0.05a
P value2	0.07	0.67		0.17	0.62
H. pylori non-eradicated BMI-NW	68.7 ± 19.7	60.8 ± 22.0	0.57	780 ± 397	653 ± 258	0.20
H. pylori non-eradicated BMI-OW	69.0 ± 21.0	64.4 ± 15.6	0.88	796 ± 221	791 ± 280	0.77
P value2	0.40	0.69		0.76	0.46

¹Mann-Whitney U test;

²Wilcoxon-signed ranks test.

^aP < 0.05 is significant; BMI: Body mass index (NW: ≤ 25, normal weight; OW: > 25, overweight); H. pylori: Helicobacter pylori.