Hepatitis B virus induces expression of cholesterol metabolism-related genes via TLR2 in HepG2 cells

Figure 3 Effects of adenovirus hepatitis B virus treatment on toll-like receptors mRNA levels in HepG2 cells. A: Adenovirus-hepatitis B virus (Ad-HBV) at 10⁵ and 10⁶ copies profoundly augmented the mRNA levels of toll-like receptor 2 (TLR2). While the concentration of Ad-HBV up to 10⁷ copies, the mRNA expression were suppressed instead. B: The mRNA of TLR4 were increased in HepG2 cells treated with Ad-HBV, which was in a dose-dependent manner. Results were representative of three similar experiments. ^aP < 0.05, ^bP < 0.01 vs control group.