Correlation of human epidermal growth factor receptor 2 expression with clinicopathological characteristics and prognosis in gastric cancer

Figure 1 Fluorescent in-situ hybridization analysis of human epidermal growth factor receptor 2 gene amplification (× 600). A: Normal human epidermal growth factor receptor 2 (HER2) gene expression: Red signals (HER2 gene), green signals [chromosome enumeration probe 17 (CEP17)], blue signals (nuclei lining dye); B: Positive HER2 gene amplification: HER2:CEP17 > 2; C: Positive HER2 gene amplification: HER2:CEP17 > 2 with clear red cluster signals observed.