Measurement of calprotectin in ascitic fluid to identify elevated polymorphonuclear cell count

Table 3 Test characteristics of ascitic calprotectin to identify > 250 polymorphonuclear leukocytes per mL ascites

	AUC (95%CI)	Best cut-off (μg/mL)	Sens (%)	Spec (%)	LR+	LR-	PPV (%)	NPV (%)	Accuracy (%)
ELISA	0.977 (0.933-0.995)	0.63	94.8	89.2	8.76	0.06	60.0	99.0	90.0
POC	0.982 (0.942-0.997)	0.51	100	84.7	6.53	0.00	52.8	100	87.7

Area under the receiver operating characteristics curve (AUC) with corresponding sensitivity (Sens), specificity (Spec), positive and negative likelihood ratio (LR+, LR-), and negative and positive predictive values (NPV, PPV) for ascitic calprotectin to identify polymorphonuclear > 250/μL. Overall accuracy was calculated using the following formula: (true positive test results + true negative test results)/total population. ELISA: Enzyme-linked immunosorbent; POC: Point-of-care.