Clinical application of microRNA in gastric cancer in Eastern Asian area

doi:10.3748/wjg.v19.i13.2019

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 7, 2013; 19(13): 2019-2027
Published online Apr 7, 2013. doi: 10.3748/wjg.v19.i13.2019

Table 3 Gastric cancer with potential predictive role of miRNAs

	Potential predictive role of miRNA
	MiRNAs of high expression	MiRNAs of low expression
Short survival time	miRNA-20b, miRNA-150[29], miRNA-142-5p[61], miRNA-375, miRNA-214[62]	miRNA-451, let7g¹, miRNA-433^1[33], miRNA-125-5p^3[63]
Lymph node metastasis	miRNA-27a[29], miRNA-650[64]	miRNA-126[65], miRNA-146a[66], miRNA-148[67], miRNA-218[68], miRNA-335[69], miRNA-429[70]
Relapse	miRNA-375[61], miRNA-451², miRNA-199-3p², miRNA-195^2[71]	miRNA-142-5p[61]
Advanced gastric cancer	miRNA-221^4[72]	miRNA-126[65], miRNA-148a[67], miRNA-218[68]
Invasion, metastasis	miRNA-223[35], miRNA-148a[73], miRNA-107[74]	miRNA-610[75], miRNA-200b^5[76], miRNA-7[77]

¹The two miRNAs also indicate short survival and lymph node metastasis, and deeper invasion;

²The three miRNAs also indicate short survival and recurrence, especially miRNA-451; ³The miRNA also indicates short survival and hepatic metastases, deeper invasion, and tumor enlargement; ⁴The miRNA also indicates lymph node metastasis and deeper invasion, and advanced gastric cancer; ⁵The miRNA also indicates lymph node metastasis and deeper invasion, and the tumor is enlarged.

Citation: Gao M, Yin H, Fei ZW. Clinical application of microRNA in gastric cancer in Eastern Asian area. World J Gastroenterol 2013; 19(13): 2019-2027
URL: https://www.wjgnet.com/1007-9327/full/v19/i13/2019.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i13.2019