Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells

Figure 6 Effects of Rh2 on protein and mRNA expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in Bxpc-3 cells. A, B: Reverse transcriptase-polymerase chain reaction was used to examine the expression of matrix metalloproteinase (MMP)-2 and MMP-9 mRNA. Rh2 (45 μmol/L) downregulated expression of MMP-2 and MMP-9 mRNA; C, D: Enzyme-linked immunosorbent assay was used to examine protein expression of MMP-2 and MMP-9. Rh2 downregulated protein expression of MMP-2 and MMP-9 in supernatants of Bxpc-3 cells in a dose-dependent manner, ^aP < 0.05 vs 0 μmol /L group.