Mitofusin-2 ameliorates high-fat diet-induced insulin resistance in liver of rats

Figure 2 High-fat diets resulted in insulin resistance in rats (n = 6). Rats were fed with high-fat diets or normal control diets for 4 wk or 8 wk. A: The level of blood glucose; B: The level of plasma insulin. C: The values of glucose infusion rate (GIR) were used to assess insulin sensitivity of rats assayed by hyperinsulinemic euglycemic clamping; D: The level of plasma total cholesterol (TC); E: The level of plasma triglyceride (TG); F: The body weight. ^aP < 0.05, ^bP < 0.01 vs normal diets; ^cP < 0.05, ^dP < 0.01 vs 4 wk.