Scolopendra subspinipes mutilans protected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1

doi:10.3748/wjg.v19.i10.1551

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 14, 2013; 19(10): 1551-1562
Published online Mar 14, 2013. doi: 10.3748/wjg.v19.i10.1551

Table 2 Effect of Scolopendra subspinipes mutilans on lung histological scoring during acute pancreatitis (mean ± SE, n = 6)

Group	Edema	Inflammation
Saline	0.2 ± 0.05	0.3 ± 0.03
AP	2.7 ± 0.02^a	2.8 ± 0.05^a
SSM 0.1 + AP	2.2 ± 0.04^a^c	2.3 ± 0.02^a^c
SSM 0.5 + AP	1.6 ± 0.03 ^a^c	1.5 ± 0.04^a^c
SSM 1 + AP	1.0 ± 0.05^a^c	0.8 ± 0.03^a^c

The results were similar in 3 further experiments.

^aP < 0.05 vs control group,

^cP < 0.05 vs cerulein treatment alone. SSM: Scolopendra subspinipes mutilans; AP: Acute pancreatitis.

Citation: Jo IJ, Bae GS, Park KC, Choi SB, Jung WS, Jung SY, Cho JH, Choi MO, Song HJ, Park SJ. Scolopendra subspinipes mutilans protected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1. World J Gastroenterol 2013; 19(10): 1551-1562
URL: https://www.wjgnet.com/1007-9327/full/v19/i10/1551.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i10.1551