Prolonged QT dispersion in inflammatory bowel disease

doi:10.3748/wjg.v19.i1.65

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2013; 19(1): 65-71
Published online Jan 7, 2013. doi: 10.3748/wjg.v19.i1.65

Table 4 Ulcerative colitis and control group, demographic, anthropometric, and laboratory values and the relationship between QT prolongation

	UC QT prolongation (-)	UC QT prolongation (+)	Control	Test values
Male, n (%)	25 (47.2)	5 (55.6)	31 (66)	χ² = 3.56, P = 0.16
Female, n (%)	28 (52.8)	4 (44.4)	16 (34)	χ² = 3.56, P = 0.16
Age (yr)	39.57 ± 11.58	48.67 ± 13.93	41.21 ± 10.55	P = 0.14
SBP (mmHg)	114.09 ± 8.73	125 ± 13.81	102.74 ± 9.93	UC QT prolongation (-) vs (+), ^aP = 0.012; UC QT prolongation (-) vs control, P = 0.51; UC QT prolongation (+) vs control, ^aP = 0.037
DBP (mmHg)	73.96 ± 6.88	74.44 ± 8.81	71.11 ± 6.55	P = 0.66
Heart rate (beats/min)	77.13 ± 13.4	71.4 ± 12.23	74.80 ± 13.25	P = 0.25
BMI (kg/m²)	25.22 ± 4.31	27.72 ± 9.11	24.77 ± 3.43	P = 0.18
WC (cm) male	94.92 ± 9.91	104.6 ± 22.67	93.19 ± 10.99	P = 0.59
WC (cm) female	92.75 ± 12.83	93.5 ± 10.96	90.68 ± 12.18	P = 0.54
QTcd (ms)	40.09 ± 2.34	55.1 ± 3.1	38.68 ± 2.25	UC QT prolongation (-) vs (+), UC QT prolongation (+) vs control, ^bP = 0.000; UC QT prolongation (-) vs control, ^bP = 0.003
FPG (mg/dL)	93.62 ± 9.02	95.11 ± 17.33	87.6 ± 10.13	P = 0.53
Total-C (mg/dL)	194.49 ± 34.31	214.33 ± 40.84	185.68 ± 37.74	P = 0.34
Triglyceride (mg/dL)	114.33 ± 53.89	120.11 ± 36.31	97.98 ± 36.74	P = 0.10
HDL-C (mg/dL)	54.62 ± 15.10	61.22 ± 14.95	58.17 ± 14.74	P = 0.38
LDL-C (mg/dL)	124.81 ± 24.41	137.552 ± 28.75	119.02 ± 24.48	P = 0.49
Insulin (μU/mL)	7.20 ± 4.54	10.88 ± 7.19	5.68 ± 3.83	UC QT prolongation (-) vs (+), ^aP = 0.031; UC QT prolongation (-) vs control, P = 0.43; UC QT prolongation (+) vs control, ^aP = 0.047
HOMA-IR	1.90 ± 1.09	2.94 ± 1.88	1.31 ± 0.94	UC QT prolongation (-) vs (+), ^aP = 0.011; UC QT prolongation (-) vs control, P = 0.51; UC QT prolongation (+) vs control, ^aP = 0.027
Uric acid (mg/dL)	4.31 ± 1.35	4.44 ± 1.29	4.01 ± 1.05	P = 0.12

^aP < 0.05,

^bP < 0.01, χ² test, Mann-Whitney U test, Kruskall-Wallis test. UC: Ulcerative colitis; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; BMI: Body mass index; WC: Waist circumference; QTcd: Corrected QT dispersion; FPG: Fasting plasma glucose; C: Cholesterol; HDL: High density lipoprotein; LDL: Low density lipoprotein; HOMA-IR: Homeostasis model assessment of insulin resistance.

Citation: Yorulmaz E, Sezgin A, Yorulmaz H, Adali G, Ciftci H. Prolonged QT dispersion in inflammatory bowel disease. World J Gastroenterol 2013; 19(1): 65-71
URL: https://www.wjgnet.com/1007-9327/full/v19/i1/65.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i1.65