Prolonged QT dispersion in inflammatory bowel disease

doi:10.3748/wjg.v19.i1.65

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2013; 19(1): 65-71
Published online Jan 7, 2013. doi: 10.3748/wjg.v19.i1.65

Table 3 Crohn’s disease and control group, demographic, anthropometric and laboratory values and the relationship between QT prolongation

	CD QT prolongation (-)	CD QT prolongation (+)	Control	Test values
Male, n (%)	23 (63.9)	2 (40)	31 (66)	χ² = 1.31, P = 0.51
Female, n (%)	13 (36.1)	3 (60)	16 (34)	χ² = 1.31, P = 0.51
Age (yr)	36.80 ± 7.79	41.33 ± 7.66	41.21 ± 10.55	P = 0.53
SBP (mmHg)	109.72 ± 13.41	105 ± 20	102.74 ± 11.93	P = 0.071
DBP (mmHg)	69.72 ± 9.40	70 ± 10	71.11 ± 6.55	P = 0.62
Heart rate (beats/min)	77.13 ± 13.4	71.4 ± 12.23	74.80 ± 13.25	P = 0.36
BMI (kg/m²)	23.78 ± 4.90	25.38 ± 3.99	24.77 ± 3.43	P = 0.57
WC (cm) male	89 ± 7.88	91 ± 6.36	90.19 ± 4.99	P = 0.14
WC (cm) female	87.23 ± 5.45	92.33 ± 7.08	90.68 ± 5.18	P = 0.19
QTcd (ms)	39.69 ± 2.32	55.4 ± 2.88	38.68 ± 2.25	CD QT prolongation (-) vs (+), CD QT prolongation (+) vs control, ^bP = 0.000; CD QT prolongation (-) vs control, ^aP = 0.049
FPG (mg/dL)	89.31 ± 6.87	93.8 ± 10.75	87.6 ± 10.13	P = 0.078
Total-C (mg/dL)	187.89 ± 39.46	189.8 ± 21.28	185.68 ± 37.74	P = 0.65
Triglyceride (mg/dL)	116.51 ± 64.85	111 ± 33.12	97.98 ± 36.74	P = 0.50
HDL-C (mg/dL)	55.4 ± 12.69	60 ± 19.19	58.17 ± 14.74	P = 0.66
LDL-C (mg/dL)	121.05 ± 32.66	118.2 ± 9.78	119.02 ± 24.48	P = 0.77
Insulin (μU/mL)	6.44 ± 3.28	10.95 ± 6.10	5.68 ± 3.83	CD QT prolongation (-) vs (+), ^aP = 0.036; CD QT prolongation (-) vs control, ^aP = 0.027; CD QT prolongation (+) vs control, P = 0.16
HOMA-IR	1.42 ± 0.75	2.56 ± 1.43	1.31 ± 0.94	CD QT prolongation (-) vs (+), ^aP = 0.026; CD QT prolongation (-) vs control, P = 0.12; CD QT prolongation (+) vs control, ^aP = 0.023
Uric acid (mg/dL)	4.09 ± 0.86	4.26 ± 1.52	4.01 ± 1.05	P = 0.95

^aP < 0.05,

^bP < 0.01, χ² test, Mann-Whitney U test, Kruskall-Wallis test. CD: Crohn’s disease; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; BMI: Body mass index; WC: Waist circumference; QTcd: Corrected QT dispersion; FPG: Fasting plasma glucose; C: Cholesterol; HDL: High density lipoprotein; LDL: Low density lipoprotein; HOMA-IR: Homeostasis model assessment of insulin resistance.

Citation: Yorulmaz E, Sezgin A, Yorulmaz H, Adali G, Ciftci H. Prolonged QT dispersion in inflammatory bowel disease. World J Gastroenterol 2013; 19(1): 65-71
URL: https://www.wjgnet.com/1007-9327/full/v19/i1/65.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i1.65