Histotype-based prognostic classification of gastric cancer

Figure 2 Muconodular, well-differentiated tubular, diffuse desmoplastic and high lymphoid response. A: Low-grade muconodular cancer with expansile growth (hematoxylin-eosin, × 20); in the inset, note tumor cells floating inside mucin, free of contact with stroma (× 400); B: intermediate-grade, locally infiltrative mucinous cancer (hematoxylin-eosin, × 200); C: massive lymphoinvasion of a high-grade mucinous cancer (podoplanin immunoperoxidase-hematoxylin, × 200); D: Diffuse anaplastic cancer invading the muscularis propria (hematoxylin-eosin, × 200), in the inset the enlargement shows cellular pleomorphism (× 400) .