Prophylaxis of chronic kidney disease after liver transplantation - experience from west China

Table 4 The risk factors of chronic kidney disease by univariate logistic regression

Clinical factors	P value	OR	95% CI
Factors before LT
Gender (female = 0, male = 1)	0.001	0.385	0.232-0.638
Ages at LT	0.001	1.048	1.025-1.072
Liver cirrhosis	0.303	1.590	0.658-3.840
End stage liver disease	0.014	1.740	1.120-2.703
HBV infection	0.327	0.756	0.432-1.323
DM	0.091	1.932	0.900-4.147
Hypertension	0.052	3.092	0.990-9.659
Renal dysfunction	0.001	3.937	2.173-7.134
HRS	0.002	3.570	1.603-7.953
Hemodialysis	0.001	4.630	1.830-11.716
TB	0.014	1.001	1.000-1.003
MELD	0.000	1.049	1.023-1.075
Factors after LT
Re-operation	0.454	1.324	0.635-2.761
Use of TAC	0.010	0.541	0.340-0.861
Use of MMF	0.003	0.520	0.336-0.805
CNI trough concentrations	0.001	2.528	1.627-3.927
AKI	0.001	3.785	2.275-6.296
Hypertension	0.001	2.972	1.619-5.455
DM	0.035	1.712	1.037-2.824
AR	0.509	1.107	0.820-1.494
CR	0.338	0.565	0.176-1.814
Graft failure	0.055	2.710	0.978-7.510
Re-transplantation	0.052	3.092	0.990-9.659
Hypertriglyceridemia	0.036	1.724	1.038-2.863
Hypercholesterolemia	0.059	1.733	0.979-3.070

OR: Odds ratios; CI: Confidence intervals; LT: Liver transplantation; HBV: Hepatitis B virus; DM: Diabetes mellitus; HRS: Hepatorenal syndrome; TB: Total serum bilirubin at baseline; TAC: Tacrolimus; MMF: Mycophenolate mofetil; AKI: Acute kidney injury; AR: Acute rejection; CR: Chronic rejection.