Histotype-based prognostic classification of gastric cancer

doi:10.3748/wjg.v18.i9.896

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2012; 18(9): 896-904
Published online Mar 7, 2012. doi: 10.3748/wjg.v18.i9.896

Table 4 Three subtypes of high lymphoid response tumors and comparison with non-high lymphoid response high-level microsatellite DNA instability cases (Pavia and Varese series)

				Cox survival analysis
						P value
	n (%)	Death rate	95% CI	HR	95% CI	Univariate	With stage
HLR⁺
EBV⁺	24 (29.6)¹	7.38	4.09-13.33	2.39	1.03-5.53	0.042	0.817
MSI-H	40 (49.4)	3.01	1.67-5.44	1
EBV^-/MSI^-	17 (21.0)	2.27	0.85-6.06	0.81	0.26-2.53	0.711	0.393
HLR^-
MSI-H	38 (48.7)²	12.29	8.24-18.33	3.64	1.78-7.47	< 0.001	0.015

¹One EBV⁺/MSI^- case omitted;

²% of all MSI-H cases, HLR⁺ or

^-. HLR: High lymphoid response; EBV: Epstein-Barr virus; MSI-H: High-level microsatellite DNA instability.

Citation: Chiaravalli AM, Klersy C, Vanoli A, Ferretti A, Capella C, Solcia E. Histotype-based prognostic classification of gastric cancer. World J Gastroenterol 2012; 18(9): 896-904
URL: https://www.wjgnet.com/1007-9327/full/v18/i9/896.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i9.896