Editorial
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 7, 2012; 18(9): 865-871
Published online Mar 7, 2012. doi: 10.3748/wjg.v18.i9.865
Table 1 Antimicrobial regimens recommended by the World Society of Emergency Surgery recommendations for treating extra-biliary community-acquired intra-abdominal infections
Antimicrobial agentsDosage
In stable, non-critical patients
With no ESBL-associated risk factorsAmoxicillin/clavulanate2.2 g every 6 h (2-h infusion time)
Ciprofloxacin400 mg every 8 h (30-min infusion time)
+
Metronidazole500 mg every 6 h (1-h infusion time)
With ESBL-associated risk factorsErtapenem1 g every 24 h (2-h infusion time)
Tigecycline100 mg LD then 50 mg every 12 h (2-h infusion time)
In critically ill patients presenting
With no ESBL-associated risk factorsPiperacillin/tazobactam9 g LD then 18 g per day via continuous infusion or 4.5 g every 6 h (4-h infusion time)
With ESBL-associated risk factorsMeropenem500 mg every 6 h (6-h infusion time)
or
Imipenem500 mg every 4 h (3-h infusion time)
+
Fluconazole600 mg LD then 400 mg every 24 h (2-h infusion time)