Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance

Figure 2 Fibroblast activation protein expression in pancreatic ductal adenocarcinoma. A: Fibroblast activation protein (FAP) expression in carcinoma cells is located mainly on the cell membrane and in the cytoplasm (× 200); B: FAP-positive fibroblasts are mainly located adjacent to carcinoma tissue (× 200); C: FAP is expressed in carcinoma cells and in fibroblasts adjacent to carcinoma tissue (× 100); D: The adjacent noncancerous pancreatic ducts show no positive staining for FAP and fibroblasts away from the tumor tissues rarely express FAP (× 200).