Routine blood tests to predict liver fibrosis in chronic hepatitis C

Table 5 Performance of simple fibrosis prediction tests for significant fibrosis (F2, F3 and F4) and extensive fibrosis (F3 and F4)

Metavir fibrosis score vs	AUC (F2, F3, F4)(95% CI)	AUC (F3, F4)(95% CI)
AAR	0.709 (0.626-0.792)	0.675 (0.607-0.743)
APRI	0.651 (0.566-0.736)	0.681 (0.613-0.749)
FibroQ	0.789 (0.720-0.857)	0.728 (0.662-0.793)
FIB-4	0.785 (0.686-0.830)	0.725 (0.659-0.791)
CDS	0.580 (0.485-0.674)	0.609 (0.537-0.680)
API	0.739 (0.660-0.818)	0.696 (0.628-0.764)
Lok’s model	0.768 (0.695-0.840)	0.721 (0.656-0.786)
Pohl score	0.523 (0.429-0.617)	0.532 (0.458-0.606)

AAR: AST/ALT ratio; APRI: AST-to-platelet ratio index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; API: Age-platelet index; CDS: Cirrhosis discriminant score; AUC: Area under the receiver operating characteristic curve.