(Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione protects rats from carbon tetrachloride-induced liver injury and fibrogenesis

Figure 1 Effect of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione on carbon tetrachloride-induced hepatitis. A: The structure of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione (SKLB010); B: Representative liver histology of the rats in each group at 24 h after carbon tetrachloride (CCl₄) injection, liver sections were stained with hematoxylin-eosin (original magnification 200 ×); C: Time course of hepatocyte necrosis after CCl₄ challenge, alanine aminotransferase (ALT) was measured in serum collected at time points as indicated. Values are presented as mean ± SD of the mean. (n = 5, ^aP < 0.05 vs the level in the model group).