Identification of colorectal cancer metastasis markers by an angiogenesis-related cytokine-antibody array

Figure 4 Vascular endothelial growth factor receptors expression in colorectal cancer cell lines. A: Soluble vascular endothelial growth factor receptor (sVEGFR)-1 expression measured by EIA is not significantly different between primary and metastatic colorectal cancer (CRC) cell lines; B: Flow cytometry of the surface expression of vascular endothelial growth factor receptor (VEGFR)-2 in human umbilical vein endothelial cells (HUVEC) and the primary CRC cell lines HCT116, Caco2 and RKO under normoxic conditions reveals a general lack of VEGFR-2 expression on the surface of CRC cells as compared to HUVEC. NS: Not significant.