Hyperpolarization-activated cyclic nucleotide-gated cation channel subtypes differentially modulate the excitability of murine small intestinal afferents

Figure 8 Immunostaining for hyperpolarization-activated cyclic nucleotide-gated cation channel 3 in intestinal primary afferent neurons. Intestinal afferents were labeled via injecting DiI into the gut wall. Note that weak hyperpolarization-activated cyclic nucleotide-gated cation channel 3 (HCN₃) immunoreactivity (green) was present in some DiI-labeled (red) dorsal root ganglia neurons. In contrast, most DiI-labeled nodose ganglia neurons were moderately stained for HCN₃.