Hyperpolarization-activated cyclic nucleotide-gated cation channel subtypes differentially modulate the excitability of murine small intestinal afferents

Figure 7 Immunostaining for hyperpolarization-activated cyclic nucleotide-gated cation channel 2 in intestinal primary afferent neurons. Spinal and vagal afferent neurons innervating the small intestine were labeled via injection of DiI (red) into the gut wall. Arrows indicate positive hyperpolarization-activated cyclic nucleotide-gated cation channel 2 (HCN₂) staining in DiI-labeled dorsal root ganglia neurons. DRG: Dissociated dorsal root ganglia; NG: Nodose ganglia.