Identification of differential gene expressions in colorectal cancer and polyp by cDNA microarray

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Feb 14, 2012 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2012; 18(6): 570-575
Published online Feb 14, 2012. doi: 10.3748/wjg.v18.i6.570

Table 4 Differentially expressed genes between polyps and colorectal cancer

Accession	Gene function	Gene tag	Ratio
			A	B
AA191692	Stratifin	SFN	2.36 ± 0.25	3.86 ± 0.11^a
H15456	Calpain 1, (mu/I) large subunit	CAPN1	8.17 ± 0.20	10.25 ± 0.24^a
AA043501	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog	MAF	1.36 ± 0.08	4.85 ± 0.27^a
AA495936	Microsomal glutathione S-transferase 1	MGST1	-2.14 ± 0.23	2.90 ± 0.16^a
H23235	Platelet-derived growth factor receptor	PDGFRA	-0.15 ± 0.31	4.81 ± 0.14^a
AA430032	Pituitary tumor-transforming 1	PTTG	4.91 ± 0.23	11.46 ± 0.18^a
N94468	Jun B proto-oncogene	JUNB	1.27 ± 0.20	11.09 ± 0.14^a
T61948	FBJ murine osteosarcoma viral oncogene B homolog	FOSB	1.37 ± 0.31	10.21 ± 0.20^a

AA460168	Growth arrest and DNA damage inducible 34	GADD34	1.07 ± 0.15	4.15 ± 0.20^a
L36870	MAP kinase kinase 4	MKK4	4.01 ± 0.23	6.93 ± 0.24^a
AA426216	Malignant cell expression-enhanced gene	LENG4	7.03 ± 0.16	8.81 ± 0.23^a
AA486219	SRp25 nuclear protein	LOC51329	2.09 ± 0.12	6.18 ± 0.23^a
AA457705	Immediate early response 3	IER3	1.94 ± 0.25	9.17 ± 0.20^a
AA485377	v-fos FBJ murine osteosarcoma viral oncogene homolog	FOS	4.03 ± 0.27	7.21 ± 0.05^a
AA463204	Pleiomorphic adenoma gene-like 1	PLAGL1	7.11 ± 0.24	-4.16 ± 0.06^a
AA434373	E74-like factor 3 (epithelial-specific )	ELF3	1.09 ± 0.29	7.03 ± 0.15^a
AI677994	Fms-associated tyrosine kinase 3 ligand	FLT3LG	1.94 ± 0.32	4.35 ± 0.02^a
AA464600	v-myc avian myelocytomatosis viral oncogene homolog	MYC	3.27 ± 0.17	8.01 ± 0.13^a

^aP < 0.05. “-” indicates down-regulation. A: Polyps vs normal mucosae; B: Colorectal cancer vs normal mucosae.

Citation: Dai YC, Zhu XS, Nan QZ, Chen ZX, Xie JP, Fu YK, Lin YY, Lian QN, Sang QF, Zhan XJ. Identification of differential gene expressions in colorectal cancer and polyp by cDNA microarray. World J Gastroenterol 2012; 18(6): 570-575
URL: https://www.wjgnet.com/1007-9327/full/v18/i6/570.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i6.570