ABO blood type, diabetes and risk of gastrointestinal cancer in northern China

Table 2 Associations between different risk factors and cancer types

Cancer type	Sex		Age		Family history		HBsAg		Diabetes
	OR1	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Esophageal	3.22	[2.42–4.28]	1.12	[1.10–1.13]	6.20	[3.03–12.68]	0.66	[0.39–1.11]	0.29	[0.15–0.54]
Gastric	1.80	[1.38–2.35]	1.08	[1.07–1.09]	9.61	[5.07–18.22]	0.72	[0.43–1.19]	2.07	[1.40–3.08]
Biliary	0.86	[0.67–1.10]	1.10	[1.09–1.11]	5.27	[2.58–10.75]	0.94	[0.56–1.58]	2.13	[1.43–3.17]
Pancreatic	1.21	[0.94–1.55]	1.08	[1.07–1.09]	6.18	[3.22–11.86]	0.72	[0.43–1.19]	2.87	[1.97–4.19]
Glioma	1.17	[0.93–1.47]	0.98	[0.97–0.99]	2.83	[1.42–5.64]	0.68	[0.42–1.09]	1.06	[0.65–1.72]
Thyroid	0.37	[0.30–0.47]	1.00	[1.00–1.01]	2.46	[1.24–4.88]	0.95	[0.61–1.47]	0.89	[0.54–1.45]

¹OR > 1 means males are more susceptible than females to cancers. Odd ratios (ORs) and respective 95% confidence intervals (CIs) were calculated using multivariable logistic regression. For each cancer, regression analysis was performed vs healthy controls. Factors including HBsAg and diabetes, as well as sex, age and family history of cancer were considered.