A pharmacodynamic model of portal hypertension in isolated perfused rat liver

doi:10.3748/wjg.v18.i5.472

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Feb 7, 2012 (publication date) through Dec 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 7, 2012; 18(5): 472-478
Published online Feb 7, 2012. doi: 10.3748/wjg.v18.i5.472

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Figure 1 Group design of pharmacological model of portal hypertension. Oil indicated was administered subcutaneously with 3 mL/kg olive oil twice weekly for 84 d, as was CCl₄ + Oil 40% (v/v) CCl₄ in olive oil; IPPRL: Isolated portal perfused rat livers; EV₅₀: Median effective velocity; PE: Phenylephrine; Ach: Acetylcholine; CEC₅₀: Median effective concentration of PE constriction; REC₅₀: Median effective concentration of Ach relaxation; HE: Hematoxylin and eosin.

Citation: Zhang T, Xu XY, Zhou H, Zhao X, Song M, Zhang TT, Yin H, Li T, Li PT, Cai DY. A pharmacodynamic model of portal hypertension in isolated perfused rat liver. World J Gastroenterol 2012; 18(5): 472-478
URL: https://www.wjgnet.com/1007-9327/full/v18/i5/472.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i5.472