Safety assessment of Bifidobacterium longum JDM301 based on complete genome sequences

Table 1 Putative antibiotic resistance genes identified in the genome of Bifidobacterium longum JDM301

Antibiotics	Antibiotic resistance genes	Product name
Bacitracin	BLJ_1636	ABC transporter-related protein
	BLJ_0984	ABC transporter-related protein
	BLJ_0923	ABC transporter-related protein
	BLJ_1055	Undecaprenyl pyrophosphate phosphatase
	BLJ_1119	Bacitracin transport ATP-binding protein bcrA
Vancomycin	BLJ_0853	VanU
	BLJ_1764	Dehydrogenase VanH
	BLJ_1084	Sensor protein vanSB
	BLJ_0707	VanSD5
	BLJ_0343	Histidine kinase VanSc3
	BLJ_0287	D-Ala: D-Lac ligase VanD
Multiple drugs	BLJ_1090	ATP-binding protein
	BLJ_1650	Lsa
	BLJ_1437	LmrB
	BLJ_0618	Multidrug export protein MepA
	BLJ_0769	Efflux transporter, RND family, MFP subunit
	BLJ_0181	Multidrug efflux protein QacB
	BLJ_1062	Multidrug export protein MepA
Chloramphenicol	BLJ_1672	Chloramphenicol resistance protein
	BLJ_1322	Chloramphenicol resistance protein
Thiostrepton	BLJ_0885	Thiostrepton-resistance methylase
Penicillin	BLJ_1301	Penicillin binding protein
Kasugamycin	BLJ_2030	S-adenosylmethionine-6-N', N'-adenosyl
		(rRNA) dimethyltransferase
Tetracycline	BLJ_0814	Tetracycline-resistance determinant tetV
	BLJ_1245	TetW
	BLJ_0594	Tetracycline resistance protein
	BLJ_1401	TetQ
Carbomycin	BLJ_1625	Carbomycin resistance protein
Sulfonamide	BLJ_1629	Dihydropteroate synthase
Tetracenomycin C	BLJ_1624	Tetracenomycin C efflux protein
Trimethoprim	BLJ_1657	dihydrofolate reductase
Macrolide	BLJ_0925	Macrolide-efflux protein
	BLJ_1936	Macrolide-efflux protein
	BLJ_0819	Macrolide-efflux protein
	BLJ_0042	Macrolide-efflux protein
	BLJ_1154	Macrolide-efflux protein variant

ABC: ATP-binding cassette; RND: Resistance-nodulation-cell division.