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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2012; 18(48): 7262-7270
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7262
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7262
Figure 3 Knockdown of Notch2 enhanced the expression and activity of matrix metallopeptidase 9.
The small interfering RNA (siRNA) mediated knockdown of Notch2 (A) and Notch2 intracellular domain (N2ICD) (B, C) was associated with a marked increase in the expression (A, B, C) and activity (D) of matrix metallopeptidase 9 (MMP9). aP < 0.05, bP < 0.01 vs the blank control groups. qPCR: Quantitative reverse transcription polymerase chain reaction.
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Citation: Guo LY, Li YM, Qiao L, Liu T, Du YY, Zhang JQ, He WT, Zhao YX, He DQ. Notch2 regulates matrix metallopeptidase 9
via PI3K/AKT signaling in human gastric carcinoma cell MKN-45. World J Gastroenterol 2012; 18(48): 7262-7270 - URL: https://www.wjgnet.com/1007-9327/full/v18/i48/7262.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i48.7262