Gardenia jasminoides attenuates hepatocellular injury and fibrosis in bile duct-ligated rats and human hepatic stellate cells

Figure 1 Gardenia jasminoides markedly improved the histology in bile duct ligation rats. Representative pictures of hematoxylin and eosin staining (magnification ×200) from rats subjected to bile duct ligation (BDL) or sham-operated rats treated with vehicle or Gardenia jasminoides. A: Sham; B: BDL + vehicle; C: BDL + Gardenia jasminoides (25 mg/kg per day); D: BDL+ Gardenia jasminoides (50 mg/kg per day); E: BDL+ Gardenia jasminoides (100 mg/kg per day); F: Scores of double-blinded assessments of liver histology with respect to fibrosis. ^bP < 0.01 vs sham; ^cP < 0.05, ^dP < 0.01 vs BDL + vehicle (n = 8).