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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2012; 18(48): 7319-7326
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7319
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7319
Table 1 Clinical and histopathologic data of the patients and expression of high mobility group-box 3 in correlation with clinicopathologic variables: High mobility group-box 3 overexpression predicts the clinical course (n = 92) (%)
| Variables | Samples | HMGB3 overexpression | P value |
| Age at surgery (yr) | |||
| ≤ 60 | 34 (36.96) | 20 (60.00) | 0.247 |
| > 60 | 58 (63.04) | 30 (51.16) | |
| Gender | |||
| Male | 61 (66.30) | 30 (50.00) | 0.649 |
| Female | 31 (33.70) | 20 (62.5) | |
| Extent of wall penetration | |||
| pT1-2 | 22 (23.91) | 6 (26.67) | 0.005 |
| pT3-4 | 70 (76.01) | 44 (63.46) | |
| Lymph node metastasis | |||
| N0 | 27 (29.3) | 5 (14.29) | 0.004 |
| N1-3 | 65 (70.65) | 45 (70.59) | |
| Tumor stage | |||
| StageI+ II | 37 (40.22) | 9 (23.21) | 0.001 |
| Stage III + IV | 55 (59.78) | 41 (56.76) | |
| Tumor localisation | |||
| Fundus gastricus and cardia | 11 (11.96) | 6 (54.55) | 0.955 |
| Gastric body | 33 (35.87) | 21 (63.64) | |
| Gastric antrum | 48 (52.17) | 23 (47.91) | |
| Histologic grade | |||
| G1 + 2 | 22 (23.91) | 9 (40.91) | 0.073 |
| G3 + 4 | 70 (76.09) | 41 (58.57) |
- Citation: Tang HR, Luo XQ, Xu G, Wang Y, Feng ZJ, Xu H, Shi YW, Zhang Q, Wu LG, Xue CQ, Wang CW, Wu CY. High mobility group-box 3 overexpression is associated with poor prognosis of resected gastric adenocarcinoma. World J Gastroenterol 2012; 18(48): 7319-7326
- URL: https://www.wjgnet.com/1007-9327/full/v18/i48/7319.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i48.7319