Magnetic resonance-based total liver volume and magnetic resonance-diffusion weighted imaging for staging liver fibrosis in mini-pigs

Table 3 Receiver operating curve analyses of total liver volume and liver apparent diffusion coefficient values for prediction of fibrosis stage ≥ 2 and ≥ 3 (%)

Cut-off	Stage differentiations	AUC	Sensitivity	Specificity
TLV 656.25 cm3	Prediction of stage ≥ 2	0.682	74.1	73.7
ADC (b = 800 s/mm2)
1.82 × 10-3 mm2/s	Prediction of stage ≥ 2	0.743	69.6	73.3
1.75 × 10-3 mm2/s	Prediction of stage ≥ 3	0.646	63.6	60.0
ADC (b = 800 s/mm2)
1.51 × 10-3 mm2/s	Prediction of stage ≥ 2	0.803	82.6	76.7
1.44 × 10-3 mm2/s	Prediction of stage ≥ 3	0.847	78.8	80.0
ADC (b = 800 s/mm2)
1.29 × 10-3 mm2/s	Prediction of stage ≥ 2	0.848	78.3	80.0
1.23 × 10-3 mm2/s	Prediction of stage ≥ 3	0.887	84.8	81.2

TLV: Total liver volume; AUC: Area under the receiver operating curve curve; ADC: Apparent diffusion coefficient.