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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 28, 2012; 18(48): 7149-7157
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7149
Published online Dec 28, 2012. doi: 10.3748/wjg.v18.i48.7149
Table 1 Primary antiviral drug resistance mutations in the polymerase gene[23]
| Domain A | Domain B | Domain C | Domain D | Domain E | Numbers of mutations | |
| Lamivudine and Telbivudine | rtV173L | |||||
| -- | rtL180M | rtM204V/I | -- | -- | 1 | |
| rtA181T/V | ||||||
| Adefovir | -- | rtA181T/V | rtN236T | -- | 1 | |
| Tenofovir | -- | rtA181T/V | rtN236T | -- | ? | |
| Entecavir | -- | rtL180M | rtM204I/V | -- | rtM250I/V | 3 |
| rtT184 | rtS202 |
- Citation: Song ZL, Cui YJ, Zheng WP, Teng DH, Zheng H. Diagnostic and therapeutic progress of multi-drug resistance with anti-HBV nucleos(t)ide analogues. World J Gastroenterol 2012; 18(48): 7149-7157
- URL: https://www.wjgnet.com/1007-9327/full/v18/i48/7149.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i48.7149