Sex-dimorphic adverse drug reactions to immune suppressive agents in inflammatory bowel disease

Figure 1 Relative percentages of male and female patients experiencing adverse drug reactions to “classical” immune suppressive agents (thiopurines, methotrexate, cyclosporine and tacrolimus) and anti-tumor necrosis factor agents. A: Adverse drug reactions (ADR) to immune suppressive agents in general; B: ADR to respective immunosuppressive agents; C: ADR to anti-tumor necrosis factor agents (anti-TNF) in general; D: ADR to respective anti-TNF agents. ¹Two-sided χ² test. Black bars: ADR present; Gray bars: No ADR.