Associations between interleukin-1 polymorphisms and gastric cancers among three ethnicities

Table 3 Genotype distributions of interleukin-1B-31, interleukin-1B-511 and interleukin-1RN gene polymorphisms among gastric cancer cases and controls from the Tibet, Hui and Han ethnicities n (%)

Genotype	Tibet				Hui				Han
	Cases	Controls	OR (95%CI)1	P value	Cases	Controls	OR (95%CI)1	P value	Cases	Controls	OR (95%CI)1	P value
IL-1B-31
TT	23 (14.84)	47 (22.38)	1		46 (29.11)	59 (28.78)	1		40 (20.30)	65 (32.18)	1
CT	81 (52.26)	112 (53.33)	1.47 (0.81-2.66)	0.208	79 (50.00)	105 (51.22	0.97 (0.58-1.62)	0.896	102 (51.77)	98 (48.52)	1.69 (1.03-2.76)	0.036
CC	51 (32.90)	51 (24.29)	2.10 (1.09-4.04)	0.027	33 (20.89)	41 (20.00)	1.03 (0.55-1.95)	0.919	55 (27.92)	39 (19.31)	2.29 (1.28-4.10)	0.005
IL-1B-511
CC	34 (21.94)	55 (26.19)	1		33 (20.89)	43 (20.98)	1		31 (15.74)	65 (32.17)	1
CT	80 (51.61)	93 (44.29)	1.37 (0.80-2.35)	0.210	88 (55.70)	110 (53.66)	1.04 (0.59-1.83)	0.888	101 (51.27)	99 (49.09)	2.16 (1.28-3.65)	0.004
TT	41 (26.45)	62 (29.52)	1.02 (0.56-1.86)	0.945	37 (23.41)	52 (25.37)	0.96 (0.50-1.84)	0.891	65 (32.99)	38 (18.81)	3.53 (1.49-8.33)	0.004
IL-1RN
L/L	129 (83.22)	185 (88.10)	1		94 (59.49)	156 (76.10)	1		166 (84.26)	171 (84.66)	1
2/L	26 (16.78)	25 (11.90)	1.50 (0.80-2.79)	0.206	64 (40.50)	49 (23.90)	2.11 (1.31-3.40)	0.002	31 (15.28)	31 (14.44)	1.03 (0.59-1.79)	0.924

¹Adjusted for age, sex, smoking status and Helicobacter pylori infection. IL: Interleukin; OR: Odds ratio.