Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice

Table 2 Expression of interleukin-1α, interleukin-2, interleukin-6, tumor necrosis factor-α, and interleukin-10 (n = 10)

Group	mean ± SD (pg/mL)
	IL-1α	IL-2	IL-6	TNF-α	IL-10
ADM + RFP	5.89 ± 2.12	6.11 ± 2.9a	10.99 ± 2.09a	9.00 ± 1.21	55.98 ± 2.43
ADM	4.63 ± 3.2	5.23 ± 2.12a	10.78 ± 3.13a	8.01 ± 1.22	54.01 ± 2.33
NS	13.21 ± 2.01c	11.35 ± 2.09c	29.55 ± 8.97c	23.1 ± 1.83c	56.67 ± 4.32
ADM + APS (50 mg/kg)	14.34 ± 1.78c	12.11 ± 3.08c	41.57 ± 6.42ac	29.97 ± 4.09c	41.23 ± 3.12ac
ADM + APS (100 mg/kg)	25.31 ± 2.98ac	19.98 ± 3.21ac	38.82 ± 5.88ac	33.23 ± 3.99ac	27.23 ± 7.68ac
ADM + APS (200 mg/kg)	22.45 ± 4.01ac	26.67 ± 7.21ac	40.99 ± 5.54ac	44.78 ± 3.98ac	24.87 ± 5.78ac
ADM + VER	7.34 ± 2.11	5.77 ± 2.11	9.34 ± 1.75a	9.11 ± 2.01	50.66 ± 1.12

^aP < 0.05 vs normal saline (NS) group;

^cP < 0.05 vs adriamycin (ADM) group. IL: Interleukin; TNF-α: Tumor necrosis factor-α; RFP: Rifampicin; APS: Astragalus polysaccharides; VER: Verapamil.