Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice

Table 1 Tumor inhibition rate and immune organ index (n = 10)

Group	Tumor weight (g)	Inhibition rate (%)	Spleen index	Thymus index
ADM + RFP	5.37 ± 1.31a	60.00	0.51 ± 0.28a	0.15 ± 0.04
ADM	5.32 ± 2.03a	60.36	0.39 ± 0.17a	0.13 ± 0.04
NS	13.42 ± 1.03	-	0.74 ± 0.21	0.15 ± 0.09
ADM + APS (50 mg/kg)	3.64 ± 1.54ac	72.88c	0.65 ± 0.22c	0.15 ± 0.05
ADM + APS (100 mg/kg)	3.57 ± 1.66ac	73.40c	0.62 ± 0.34c	0.20 ± 0.06c
ADM + APS (200 mg/kg)	3.01 ± 1.95ac	77.57c	0.67 ± 0.20c	0.47 ± 0.12ac
ADM + VER	4.75 ± 1.86a	69.45	0.50 ± 0.17a	0.13 ± 0.03

^aP < 0.05 vs normal saline (NS) group;

^cP < 0.05 vs adriamycin (ADM) group. RFP: Rifampicin; APS: Astragalus polysaccharides; VER: Verapamil.