Protective role of metalloproteinase inhibitor (AE-941) on ulcerative colitis in rats

Table 3 Colonic mucosal mRNA expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 (mean ± SD)

Time	Control group		Model group		AE-941 group
	MMP-2	MMP-9	MMP-2	MMP-9	MMP-2	MMP-9
7th day	0.0062 ± 0.0017	0.0068 ± 0.0096	0.8563 ± 0.1132a	0.9936 ± 0.1187a	0.7509 ± 0.0693	0.8375 ± 0.1054
21st day	0.0056 ± 0.0012	0.0071 ± 0.0134	0.6048 ± 0.0522ae	0.6873 ± 0.0472ae	0.3983 ± 0.0218c	0.5179 ± 0.0305c
56th day	0.0058 ± 0.0015	0.0069 ± 0.0011	0.4163 ± 0.0330ag	0.4328 ± 0.0257ag	0.1093 ± 0.0072c	0.2673 ± 0.0210c

^aP < 0.05 vs control group;

^cP < 0.05 vs model group;

^eP < 0.05 vs day 7 timepoint;

^gP < 0.05 vs day 21 timepoint. MMP: Matrix metalloproteinase.