Protective role of metalloproteinase inhibitor (AE-941) on ulcerative colitis in rats

Table 2 Disease activity index and colonic mucosa damage index of three groups on different time (mean ± SD)

Time	Control group		Model group		AE-941 group
	DAI	CMDI	DAI	CMDI	DAI	CMDI
7th day	0.06 ± 0.14	0.00 ± 0.00	2.89 ± 0.00a	4.83 ± 0.55a	2.76 ± 0.32	4.74 ± 0.39
21st day	0.00 ± 0.00	0.00 ± 0.00	2.09 ± 0.25a	3.03 ± 0.42a	1.55 ± 0.28c	2.08 ± 0.46c
56th day	0.00 ± 0.00	0.00 ± 0.00	1.52 ± 0.30a	1.60 ± 0.35a	0.59 ± 0.19c	0.86 ± 0.37c

^aP < 0.05 vs control group;

^cP < 0.05 vs model group. DAI: Disease activity index; CMDI: Colonic mucosa damage index.