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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 21, 2012; 18(47): 6981-6986
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.6981
Published online Dec 21, 2012. doi: 10.3748/wjg.v18.i47.6981
Genotype (n) | GG vs others | ||||
CC | CG | GG | OR (95%CI) | P value | |
Controls (465) | 197 | 225 | 43 | Ref. | - |
Age of onset | |||||
≤ 20 (27) | 12 | 9 | 6 | 2.80 (1.07-7.32) | 0.041 |
21 ≤ (133) | 50 | 66 | 17 | 1.44 (0.791-2.62) | 0.25 |
Clinical type | |||||
Not continuous (98) | 34 | 47 | 17 | 2.06 (1.13-3.77) | 0.029 |
Continuous (71) | 32 | 30 | 9 | 1.43 (0.662-3.07) | 0.39 |
Extension | |||||
Not total colitis (93) | 31 | 46 | 16 | 2.04 (1.09-3.80) | 0.040 |
Total colitis (78) | 35 | 32 | 11 | 1.61 (0.792-3.28) | 0.22 |
Max UCDAI score | |||||
≤ 8 (60) | 20 | 28 | 12 | 2.45 (1.23-4.93) | 0.022 |
9 ≤ (106) | 44 | 49 | 13 | 1.37 (0.716-2.63) | 0.37 |
Hospitalization | |||||
None (106) | 41 | 45 | 20 | 2.28 (1.29-4.05) | 0.0090 |
One time ≤ (60) | 25 | 30 | 5 | 0.892 (0.350-2.28) | 1.00 |
Response to treatment | |||||
Steroid-dependent (34) | 13 | 17 | 4 | 1.31 (0.440-3.89) | 0.54 |
Steroid-refractory (46) | 18 | 23 | 5 | 1.20 (0.449-3.19) | 0.79 |
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Citation: Hayashi R, Tahara T, Yamaaki T, Saito T, Matsunaga K, Hayashi N, Fukumura A, Ozaki K, Nakamura M, Shiroeda H, Tsutsumi M, Shibata T, Arisawa T. -449 C>G polymorphism of
NFKB1 gene, coding nuclear factor-kappa-B, is associated with the susceptibility to ulcerative colitis. World J Gastroenterol 2012; 18(47): 6981-6986 - URL: https://www.wjgnet.com/1007-9327/full/v18/i47/6981.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i47.6981