Schizandra arisanensis extract attenuates cytokine-mediated cytotoxicity in insulin-secreting cells

Figure 3 The anti-apoptotic effect of the ethanolic extract of Schizandra arisanensis. A: The viability of BRIN BD11 cells was determined after 48 h of cytokine treatment in the presence or absence of the ethanolic extract of Schizandra arisanensis (SA-Et); B: Cell cycle of BRIN BD11 cells was determined after 48 h of cytokine treatment in the presence or absence of the SA-Et. Data are presented as the mean ± SE, n = 4. ^aP < 0.05, ^bP < 0.01 vs the control; C: Both full and cleaved forms of caspase-3 protein were analyzed by Western blot after 24 h of cytokine treatment in the presence or absence of the SA-Et. A representative from three experiments is shown. IL-1β: Interleukin 1β; IFN-γ: Interferon-γ.