Utility of faecal calprotectin analysis in adult inflammatory bowel disease

Table 1 Correlation of faecal calprotectin with endoscopic findings, histology and clinical indices, when available

Ref.	Patient population	Endoscopic assessment score	Correlation coefficient with endoscopy (r)	Correlation coefficient with histology	Correlation with clinical index (r)
Røseth et al[6]	UC	MAYO	0.57	NA	NA
D'Incà et al[8]	CD	SES-CD	0.48	r = 0.12	NA
D'Incà et al[8]	UC	MAYO	0.51	r = 0.32	NA
Sipponen et al[24]	CD	CDEIS	0.73	NA	0.397(CDAI)
Schoepfer et al[27]	CD	SES-CD	0.75	NA	NA
Jones et al[28]	CD	SES-CD	0.45	NA	0.23 (CDAI)
Sipponen et al[31]	CD	SES-CD	0.64	0.56 (exchange ileal only disease)	0.32 (CDAI)
Sipponen et al[40]	CD	CDEIS	0.83	0.52 (exchange ileal only disease)	NA
Langhorst et al[48]	UC	MAYO	0.49	NA	NA
Langhorst et al[48]	CD	SES-CD	0.35	NA	NA
Hanai et al[63]	UC	Matts	0.81	NA	0.68 (CDAI)
Schoepfer et al[64]	UC	Rachmilewitz	0.83	NA	NA

NA: Not available; MAYO: Mayo score[65]; SES-CD: Simplified endoscopic activity score for Crohn’s disease (CD)[66]; CDEIS: Crohn’s disease endoscopic index of severity[67]; CDAI: Crohn’s disease activity index[68]; Matts: Matts grading[69]; UC: Ulcerative colitis.