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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 7, 2012; 18(45): 6577-6586
Published online Dec 7, 2012. doi: 10.3748/wjg.v18.i45.6577
Published online Dec 7, 2012. doi: 10.3748/wjg.v18.i45.6577
Figure 4 Immunohistochemical analysis and assessment of phospho Akt positivity based on molecular alterations in gastric cancer tissues.
A: Gastric adenocarcinoma showing phospho Akt (pAkt) positivity. Original magnification, ×200; B: pAkt expression significantly correlates with human epidermal growth factor receptor 2 (HER2) overexpression (P < 0.01) but not with phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (PIK3CA) mutations (P = 0.37) or Epstein-Barr virus (EBV) infection (P = 0.69).
- Citation: Sukawa Y, Yamamoto H, Nosho K, Kunimoto H, Suzuki H, Adachi Y, Nakazawa M, Nobuoka T, Kawayama M, Mikami M, Matsuno T, Hasegawa T, Hirata K, Imai K, Shinomura Y. Alterations in the human epidermal growth factor receptor 2-phosphatidylinositol 3-kinase-v-Akt pathway in gastric cancer. World J Gastroenterol 2012; 18(45): 6577-6586
- URL: https://www.wjgnet.com/1007-9327/full/v18/i45/6577.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i45.6577