Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients

Table 1 Clinicopathological features and the expression of lysine specific demethylase 1 in 198 hepatocellular carcinoma patients

Characteristics	n	LSD1 (%)		P value
		High expression	Low expression
Gender
Male	101	58	43
Female	97	54	43	NS
Age (yr)
≥ 50	112	61	51
< 50	86	51	35	NS
Tumor stage
T1	39	5	34
T2	42	21	21
T3	76	47	29
T4	41	39	2	< 0.001
Tumor grade
G1	45	9	34
G2	114	63	51
G3	39	38	1	< 0.001
Growth pattern
Trabecular	147	84	63
Nontrabecular	51	28	23	NS
Cirrhosis
Yes	151	87	64
No	47	25	22	NS
Underlying liver disease
Alcoholic	21	15	6
Hepatitis B	136	74	62
Hepatitis C	30	17	13
Unknown	11	6	5	NS

LSD1: Lysine specific demethylase 1; NS: Not significant.