Value of adipokines in predicting the severity of acute pancreatitis: Comprehensive review

Table 3 Summary of the experimental studies on the prognostic value of adipokines in rats

Study	Groups	n	Leptin, ng/mL	P value
Konturek et al[30]	AP	6-8	7.5 (4.3-18.4) 2.1 (1.0-11.8)	P < 0.011
	Controls	6-8
Yavuz et al[31]	AP	10	1.92 ± 0.1
	CP	10	1.86 ± 0.13
	Controls	10	0.78 ± 0.12	P < 0.001
Kerem et al[32]	AEP	30		P < 0.0012
	ANP	30
	Controls	30		P = 0.027 and P < 0.001

AP: Acute pancreatitis; CP: Chronic pancreatitis; AEP: Acute edematous pancreatitis; ANP: Acute necrotizing pancreatitis; CIP: Caerulein-induced pancreatitis.

¹The induction of CIP resulted in a significant increase of plasma levels of leptin;

²At 12 h leptin levels in ANP was higher than in controls, at 24 and 48 h leptin levels in AEP and ANP were higher than in controls.